Mesothelioma Information

Below is a list of all clinical trials in the United States for mesothelioma listed by the National Cancer Institute.  See their clinical trials web page to refine your search by location, type or drug, phase, and so on.  This list is current as of April 9, 2008.

1.  Suberoylanilide Hydroxamic Acid (SAHA) Versus Placebo in Advanced Malignant Pleural

Mesothelioma
   
Phase III, Phase II

MK0683-014, NCT00128102

2. Carboplatin, Bevacizumab and Pemetrexed in the First-Line Treatment of Patients With MPM
 
Phase II, Phase I
   
MCC-14896
USFIRB#105715, AVF3483s, NCT00604461

  
Last Modified: 11/2/2007     First Published: 1/1/1999  
 
3.  Phase II Study of Antineoplastons A10 and AS2-1 in Patients With Stage IV Mesothelioma
 
Phase II
   
BC-MA-2
NCT00003508
 
 
Last Modified: 5/25/2007     First Published: 3/24/2006  

4. Phase II Study of AZD2171 in Patients With Malignant Pleural, Peritoneal, or Tunica

Vaginalis Mesothelioma That is Not Amenable to Curative Surgery

Phase II
  
UCCRC-14203B
NCI-7103, 7103, NCT00309946

 
5.  Cisplatin, Pemetrexed and Bevacizumab for Untreated Malignant Mesothelioma AVF3442S
NCT00295503

  
Last Modified: 4/1/2008     First Published: 4/6/2007  
  

6. Phase II Study of Pazopanib Hydrochloride in Patients With Malignant Pleural Mesothelioma
 
 
Phase II
 
NCCTG-N0623
N0623, NCT00459862

Last Modified: 4/5/2008     First Published: 7/24/2007  
  

7. Phase II Study of Dasatinib in Patients With Previously Treated Malignant Mesothelioma
 
Phase II

  
CALGB-30601
CALGB-30601, CALGB 30601, NCT00509041
 
Last Modified: 9/19/2007     First Published: 7/1/2002  
  

8.  Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion

in Subjects with Pulmonary and Pleural Malignancies
 
Phase I

NCI-02-C-0205J
NCI-5270, 5270, NCT00041158

Last Modified: 12/21/2007     First Published: 11/22/2004  
  

9.  Phase I Study of FR901228 (Depsipeptide) and Flavopiridol in Patients With Advanced

Primary Lung or Esophageal Cancer, Malignant Pleural Mesothelioma, or Lung or Pleural

Metastases
 
Phase I
   
NCI-05-C-0010
5987, NCI-5987, NCT00098644

10. 
Gene Therapy for Pleural Malignancies
 
Phase I

803776
UPCC 03505, NCT00299962

11. A Phase I Study of BMS-690514 in Patients With Advanced or Metastatic Solid Tumors
  
Phase I
  
CA187-002
NCT00329004
 
Last Modified: 7/19/2007     First Published: 9/10/2006  
  

12.  Phase I Study of Anti-Mesothelin Monoclonal Antibody MORAb-009 In Patients With

Recurrent Advanced Mesothelin-Expressing Tumors
 
Phase I
 
NCI-06-C-0196
NCI-P6942, MORAb-009-001, NCT00325494

Last Modified: 12/21/2006     First Published: 11/3/2006  
  

13.  Phase I Pilot Study of Wilms Tumor-1 Analog Peptide Vaccine and Sargramostim (GM-CSF)

in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung

Cancer, or Mesothelioma
 
Phase I
  
MSKCC-06085
NCT00398138
  

14.  Cisplatin, Imatinib Mesylate, and Pemetrexed in Malignant Mesothelioma Patients
 
Phase I
  
2005-0288
NCT00402766
 
  

15.  Phase I Study Using Sunitinib Plus Radiation Therapy for Cancer Patients
 
 
Phase I
   
06C.549
NCT00437372

16.  Oxaliplatin and Paclitaxel Plus Bevacizumab in Advanced Peritoneal Carcinomatosis
 
Phase I
  
2006-1068
NCT00491855
  

17.  A Study To Find the Best Dose of SU011248 When Given With Pemetrexed, Pemetrexed and

Cisplatin Or Pemetrexed and Carboplatin in Patients With Advanced Solid Tumors
 
Phase I
   
A6181084
NCT00528619

18.  Pharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in

Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural

Mesothelioma

Phase I
   
CLBH589B2109
NCT00535951

 Last Modified: 3/28/2008     First Published: 12/14/2007  
 

19.  Phase I Study of SS1(dsFv)-PE38 Immunotoxin in Combination With Pemetrexed Disodium and

Cisplatin in Patients With Unresectable Malignant Epithelial Pleural Mesothelioma
 
 
Phase I
      
NCI-08-C-0026
08-C-0026, CAT-5001-1001, NCT00575770
  
20.  Study of Safety and Tolerability of Intravenous CRS-207 in Adults With Selected

Advanced Solid Tumors Who Have Failed or Who Are Not Candidates for Standard Treatment
 
Phase I
   
VAC07001
NCT00585845

21.  Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide
 
Phase I
      
AAAC3255
NCT00629343

22.  Vibration Response Imaging (VRI) in Lung Cancer Patients
 
No phase specified
 
2006-0668
NCT00506467

23.  Validation of a Novel Thoracic Neoplasm Radiotherapy Image Guidance Technique: A Pilot

Study
 
No phase specified

HSC-2007-0109
NCT00585819